12 results
diagnosis differential oncology anemia hemeonc management alkaline arterial biliary cholangitis cirrhosis coagulation dic disorders disseminated embolism emergencies extravascular hemolysis hemolytic
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... microangiopathy: Thrombotic thrombocytopenic ... hemoglobinuria (PNH ... #Causes #differential ... #diagnosis #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Causes of Thrombocytopenia ... Diagnosis and Workup ... not required in all ... or if a primary hematologic ... #Workup #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... protein C and S Pathophysiology ... Treat primary cause ... #Disseminated #Intravascular ... treatment #management #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
considered in all ... Heparin-induced thrombocytopenia ... - Disseminated intravascular ... Venous #Arterial #pathophysiology ... #hematology #differential
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Most cases diagnosed ... membrane into the CNS ... collection with EDTA Pathophysiology ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
for Thrombotic Thrombocytopenic ... decrease in most cases ... reflection of intravascular ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... obstruction • ALP ... cholangitis #diagnosis #workup ... #hepatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... -> AML: Blast crises ... count ↑ PLT • ↑ PBS ... infiltrates (anemia, thrombocytopenia ... #Leukemia #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... platelet count (thrombocytopenia ... IDUS) • Immune Thrombocytopenia ... Workup: • Complete ... Syndromes #diagnosis #hematology
Anemia of Hospitalization - Pathophysiology Why does the Hgb/Hct drop in the first two days during hospitalization? Interestingly,
Hospitalization - Pathophysiology ... a drop in your pts ... from blood to the extravascular ... phlebotomy/ blood work ... #pathophysiology
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