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diagnosis rheumatology syndrome treatment antinxp2 antinxp2dm atlas basics coagulation dermatomyositis dic disseminated dress effects hemophagocytic hlh intravascular key lactated lesions
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison Composition of LR: • Sodium 130 mEq/L •
Normal Saline (NS ... Composition of NS ... Normal Saline (NS ... Normal #Saline #NS ... #comparison #pharmacology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
• Facial Edema ... in 70% of cases ... withdrawal • Mild disease ... DRESS #Syndrome #dermatology ... #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Severe Liver Disease ... Treat primary cause ... Coagulation #diagnosis #causes ... #treatment #management ... #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... Xerostomia • Dental caries ... Nephrogenic DI Hematologic ... lubricants • Pharmacologic ... #Diagnosis #Management
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
blisters containing pus ... Rule out other causes ... osteoarticular and skin disease ... #diagnosis #management ... #Dermatology
Primary Dermatological Lesions Primary lesions are physical changes in the skin considered to be caused directly by
considered to be caused ... directly by the disease ... specific to a single disease ... area of dermal oedema ... #Diagnosis #Dermatology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment Primary HLH: - HLH-94 Protocol • Dexamethasone
(depending on CNS ... or autoimmune disease ... for refractory disease ... HLH #Treatment #management ... #hematology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
Pts have more ... Muscle atrophy may cause ... had more severe disease ... Dermatomyositis #diagnosis #management ... dermatology
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