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diagnosis rheumatology dermatology differential syndrome treatment sle vasculitis erythematosus hcq hivaids hydroxychloroquine idsa neurology opportunistic prevention systemic table activation adverseeffects
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... hemoglobinuria (PNH ... usually IgG) (e.g. lupus ... Extravascular #Causes ... differential #diagnosis #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
SLE) - Viral infections ... deficiencies - PNH ... APLS • Acute Infectious ... Pigmented Purpuric Dermatosis ... Differential #Diagnosis #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
fibromyalgia) • Infections ... Malignancy (e.g. hematologic ... lower extremity edema ... • May involve PNS ... activation and/or medications
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Cerebrovascular Disease ... autoantibodies that will cause ... #neurology #rheumatology ... cerebritis #diagnosis #management
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
200ng/mL Best indications ... • Special cases ... Measurement #SLE #rheumatology ... #pharmacology # ... levels #lupus #management
Kawasaki Disease (KD) - Diagnosis and Management Summary Kawasaki Disease (KD) is the most common vasculitis of
Mucositis, Rash, Hand edema ... , Cough • +/-Nausea ... cæxist with other infections ... palms or soles, edema ... KD #vasculitis #rheumatology
Hydroxychloroquine - Risks and Benefits in Lupus Benefits: ↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
and Benefits in Lupus ... Benefits: ↓ Disease ... Thrombosis, ↓ Severe infection ... recommended with other medications ... #pharmacology #
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
Capitis - Skin Disease ... : Discoid lupus ... Scarring Alopecia: Lupus ... of any comorbid disease ... Scaling, pustules, crusts
Erythemas Summarized Erythema ab igne • A dermatosis that results from repeated exposure to heat (fires, heating
Erythema ab igne • A dermatosis ... autoimmune conditions, medications ... early localized disease ... idiopathic, and medications ... differential #diagnosis #dermatology
A quick infographic on various pearls about atopic dermatitis, a disease with an increasing burden on
, a disease with ... risk factors, management ... This disease imposes ... #management #medications ... treatment #diagnosis #causes
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