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differential management rheumatology syndrome algorithm comparison oncology generalized photo systemic cold dermatomyositis lesions primary pruritus rash activation agep agglutinin alkaline
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Screen for secondary ... causes of eosinophilia ... symptoms (eg, skin ... #Differential #diagnosis ... #hematology #eosinophilia
Hypereosinophilia Syndrome (HES) - Diagnosis and Management Definition: An absolute eosinophil count (AEC) greater than 1500 and
Syndrome (HES) - Diagnosis ... than 1500 and clinical ... with blood eosinophilia ... Secondary Causes ... #diagnosis #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... purple, hemorrhagic skin ... - Hemolytic anemia ... #hematology #rheumatology ... #nonpalpable #dermatology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Generalized Differential Diagnosis ... Systemic and Primary Causes ... renal failure/uremia ... Pruritus #primary #secondary ... #generalized #dermatology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
• Facial Edema ... in 70% of cases ... Criteria for Diagnosis ... Skin involvement ... DRESS #Syndrome #dermatology
Scleroderma Like Conditions - Differential Diagnosis Eosinophilic Fasciitis: - Orange peel induration (peau d'orange) of proximal extremities
- Differential Diagnosis ... Systemic Fibrosis: - Secondary ... #Differential #Diagnosis ... #comparison #table ... #dermatology
Pustular Skin Lesions - Differential Diagnosis Framework What are pustules? • Pustules < 5-10 mm + pus • Material
- Differential Diagnosis ... Eosinophilic folliculitis ... Secondary syphilis ... #Differential #Diagnosis ... #Dermatology
Eczematous Skin Rash - Differential Diagnosis Algorithm Eczematous - Pruritic/Scaly/Erythematous lesions. Usually poorly demarcated • Atopic Dermatitis
Eczematous Skin ... Secondary to venous ... pigmentation, edema ... Eczematous #SkinRash #dermatology ... #Algorithm #causes
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
decades of life Causes ... and clinical associations ... neutrophils and eosinophils ... #rheumatology # ... comparison #table
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... Headaches • Pale skin ... and petechiae Causes ... #oncology #hematology ... #diagnosis #management
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