12 results
DRESS Syndrome vs SJS/TEN
DRESS
 • Latency: 2-8 weeks
 • Rash: Morbilliform
 • Mucosal involvement: 50% have
: 2-8 weeks • Rash ... biopsy: Dermal edema ... : 4-28 days • Rash ... TEN #comparison #table ... #dermatology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Eosinophilia and Systemic ... extensive skin rash ... • Facial Edema ... in 70% of cases ... #Syndrome #dermatology
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
Rash Secondary ... characterized by a systemic ... ▪ “Rash” (75% ... resembling rashes caused ... Clinical #Photo #Dermatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... Classified among the secondary ... (CNS) dysfunction ... Petechial or purpuric rash ... Diagnosis #Management #Hematology
Approach to Elevated Tryptase - Differential Diagnosis Framework

The DDx of elevated tryptase can be broken down
into a 4-pass system ... pass = Dangerous secondary ... Chronic & Rx-related Secondary ... • Mast cell activation ... Differential #Diagnosis #hematology
Eczematous Skin Rash - Differential Diagnosis Algorithm
Eczematous - Pruritic/Scaly/Erythematous lesions. Usually poorly demarcated
 • Atopic Dermatitis
Eczematous Skin Rash ... Secondary to venous ... pigmentation, edema ... Eczematous #SkinRash #dermatology ... Diagnosis #Algorithm #causes
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
sequestration and activation ... without other cause ... with pulmonary edema ... Transfusion #Reactions #hematology ... diagnosis #comparison #table
Erythemas Summarized
Erythema ab igne
 • A dermatosis that results from repeated exposure to heat (fires, heating
(cutaneous or systemic ... Rash is usually ... multiforme • Acute systemic ... Erythemas #comparison #table ... differential #diagnosis #dermatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... lower extremity edema ... proteinuria, dependent edema ... • May involve PNS ... Chronic B-cell activation
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
an underlying cause ... frequently affected systems ... Better call hematology ... JAK2 V617F) and MPNs ... Algorithm #workup #hematology