23 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
leakage of RBC's secondary ... deficiencies - PNH ... Differential #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
Rash Secondary ... characterized by a systemic ... ▪ “Rash” (75% ... resembling rashes caused ... Clinical #Photo #Dermatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
of Systemic Lupus ... autoantibodies that will cause ... anticoagulants (for secondary ... APS), Secondary ... #neurology #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Classified among the secondary ... (CNS) dysfunction ... Petechial or purpuric rash ... Diagnosis #Management #Hematology ... #Rheumatology
Eczematous Skin Rash - Differential Diagnosis Algorithm
Eczematous - Pruritic/Scaly/Erythematous lesions. Usually poorly demarcated
 • Atopic Dermatitis
Eczematous Skin Rash ... Secondary to venous ... pigmentation, edema ... Eczematous #SkinRash #dermatology ... Diagnosis #Algorithm #causes
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
everywhere) 2) A rash ... rosacea) 3) Limb oedema ... 6) An annular rash ... #system #erythematosus ... #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... Malignancy (e.g. hematologic ... lower extremity edema ... • May involve PNS ... Erythematosus #Diagnosis #Rheumatology
Approach to Elevated Tryptase - Differential Diagnosis Framework

The DDx of elevated tryptase can be broken down
into a 4-pass system ... pass = Dangerous secondary ... Chronic & Rx-related Secondary ... Mastocytosis • Other hematologic ... Differential #Diagnosis #hematology
Erythemas Summarized
Erythema ab igne
 • A dermatosis that results from repeated exposure to heat (fires, heating
(cutaneous or systemic ... Rash is usually ... multiforme • Acute systemic ... Erythemas #comparison #table ... differential #diagnosis #dermatology
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
an underlying cause ... frequently affected systems ... Better call hematology ... JAK2 V617F) and MPNs ... Algorithm #workup #hematology