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diagnosis rheumatology differential treatment cardiology dermatology algorithm erythematosus lupus renal sle systemic activation anthracycline antinxp2 antinxp2dm autoimmune behcet behcets capillary
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Neoplastic / Hematologic ... Autoimmune / Inflammatory ... Obstructive Pulmonary Disease ... Myasthenia Gravis Pharmacologic ... Chronic Fatigue Syndrome
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... autoantibodies that will cause ... Treatment: • Inflammatory ... cerebritis #diagnosis #management
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
disequilibrium syndrome ... irrigation • Management ... Kidney stones caused ... Diuresis #Nephrology #Pharmacology ... #Medications #Table
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome ... by case) • Surgery ... #Syndrome #Treatment ... #management #pharmacology ... #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
background of a highly inflammatory ... release of pro-inflammatory ... nervous system (CNS ... #Diagnosis #Management ... #Hematology #Rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
(25-75%): Inflammatory ... basal ganglia, CNS ... meningitis), MCC CNS ... #diagnosis #management ... signs #symptoms #rheumatology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
a rare chronic inflammatory ... blisters containing pus ... Rule out other causes ... osteoarticular and skin disease ... diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
photosensitivity, inflammatory ... Malignancy (e.g. hematologic ... lower extremity edema ... proteinuria, dependent edema ... • May involve PNS
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Gastrointestinal inflammatory ... DDX - Other causes ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... hypogammaglobulinemia #immunology #hematology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
diseases with pulmonary ... hematuria) • Inflammatory ... eye disease: scleritis ... Goodpasture's cause ... differential #diagnosis #management
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