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diagnosis differential rheumatology management cns dermatology alice arterial autoimmune bee behcet brain cerebritis disease embolism erythematosus lupus myopathy myositis noninflammatory
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
CNS Ring-Enhancing ... Diagnosis- Compatible syndrome ... , may also see skin ... differential #diagnosis #causes ... #radiology #neurology
Alice in Wonderland Syndrome What? Metamorphophsia - Distortions of the visual perceptions with changes in size (micro
in Wonderland Syndrome ... • CNS: parietal ... (Many causes!) ... encephalitis) • Brain lesions ... #diagnosis #neurology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
response to local skin ... injury) • Neurologic ... retinal damage) • Skin ... test (this is a skin ... signs #symptoms #rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... lesions that result ... Kasabach-Merritt syndrome ... deficiencies - PNH ... Gardner-Diamond syndrome
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
Non-inflammatory Causes ... nervous system (CNS ... Non-inflammatory causes ... LHON) plus MRI lesions ... #neurology #noninflammatory
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Testosterone - Coumadin skin ... • Nephrotic Syndrome ... atherosclerotic lesions ... coagulation and other causes ... pathophysiology #hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
bone, joint, and skin ... blisters containing pus ... lesions + Rheumatic ... Rule out other causes ... #Rheumatology #
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... autoantibodies that will cause ... Erythematosus #SLE #CNS ... #neurology #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
, neurologic, and ... cognitive impairment, neurologic ... tract, and often causes ... vasculitis • Behcet syndrome ... vasculitis • Cogan syndrome
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
) • Anti-Mi2 (skin ... lesions) • Anti-TIF1 ... aspiration > 50% of pts ... statins - probably caused ... Myositis #Myopathy #rheumatology
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