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diagnosis differential rheumatology infections infectiousdiseases neurology pulmonary treatment aids cerebritis clinical crypto dermatology emergencies erythematosus fungal hemeonc hiv lesions lupus
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
CNS Ring-Enhancing ... + MRI lesions + ... toxo IgG • CNS ... 30% present w/ CNS ... @AnnKumfer #CNS
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... autoantibodies that will cause ... thrombosis and/or blood-brain ... Erythematosus #SLE #CNS
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
, Cryptococcal pneumonia ... Pneumonia: • 3 syndromes ... nodules, plaques) Cryptococcus ... of a "flu-like syndrome ... Lymphadenopathy, CNS
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal Syndromes ... recent DAN) • EMG/NCS ... Goodpasture's cause ... sparing of the lung ... differential #diagnosis #management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Parotid swelling CNS ... nervous system (CNS ... • 8%-27% for CNS ... MALT Lymphoma • Lung ... Diagnosis #Management
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
blisters containing pus ... involve anterior chest ... Rule out other causes ... - MRI: inflammation ... diagnosis #management
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
): - Hematologic ... Treat underlying cause ... interventional radiology ... ) - Symptoms: CNS ... ) - Symptoms: CNS
Cryptococcal meningitis on T2 MRI 30 M from sub-Saharan Africa presents w/ progressive Headache x1 mo, +neck
on T2 MRI 30 M ... low glucose) CNS ... Nausea & vomiting ... #Brain #clinical ... #radiology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
especially the CNS ... MC: CNS CSF: • ... • Sinusitis • Brain ... change in the lungs ... Fungal #Diagnosis #Management
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