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diagnosis differential neurology management pathophysiology pediatrics peds ringenhancing autoimmune behcet cerebritis childhood dermatology disease embolism erythematosus fever floppy hypotonic immunecompromised
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
CNS Ring-Enhancing ... + toxo IgG • CNS ... 30% present w/ CNS ... : • CNS Lymphoma ... @AnnKumfer #CNS
Algorithm for evaluating multiple ring-enhancing lesions in immunocompetent (HIV negative) #ringenhancing #lesions #cns #brain #diagnosis #differential #algorithm
Algorithm for evaluating ... ring-enhancing lesions ... ringenhancing #lesions ... #cns #brain #diagnosis ... #causes #radiology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
atherosclerotic lesions ... considered in all cases ... coagulation and other causes ... - COVID-19 - PNH ... pathophysiology #hematology
Childhood Immunization Schedule: Why we immunize • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
replicates within CNS ... invade URT & via hematologic ... induces vascular & CNS ... CNS and hematologic ... persists as skin lesions
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... autoantibodies that will cause ... thrombosis and/or blood-brain ... Erythematosus #SLE #CNS ... #neurology #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
basal ganglia, CNS ... meningitis), MCC CNS ... Vascular Disease: Arterial ... collaboration • CNS ... signs #symptoms #rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
hemorrhagic skin lesions ... deficiencies - PNH ... gangrenosum • Bacterial ... Differential #Diagnosis #hematology ... #rheumatology #
Common MRI Sequences - Basic MRI Brain Interpretation • T1 Sequence - T1 is for anatomy.
Contrast material ... barrier- but masses ... hematomas and pus ... in many other lesions ... MRI #Sequences #Radiology
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm Structural Defect - Asplenia/HypospIenism • Bacteremia/Septic
Causes of Fever ... Differential Diagnosis Algorithm ... jirovecii • CNS ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
syndrome • Coronary arteries ... tract, and often causes ... Thrombosis and arterial ... chorioretinitis, CNS ... Differential #Diagnosis #Rheumatology
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