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diagnosis management differential cns dermatology mri neurology algorithm antiphospholipid apls arthritis behcet cerebritis cryofibrinogenemia disease embolism erythematosus gout gouty hypercoagulable
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
• Nephrotic Syndrome ... considered in all cases ... coagulation and other causes ... - COVID-19 - PNH ... pathophysiology #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Kasabach-Merritt syndrome ... deficiencies - PNH ... Gardner-Diamond syndrome ... Differential #Diagnosis #hematology ... #rheumatology #
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
Diagnosis- Compatible syndrome ... Infectious: • Bacterial ... RingEnhancing #Lesions #Brain ... differential #diagnosis #causes ... #radiology #neurology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... autoantibodies that will cause ... thrombosis and/or blood-brain ... #neurology #rheumatology
Leigh Syndrome History: 19-month-old girl with hypotonia, developmental delay, failure to thrive, and bilateral optic disc
Leigh Syndrome ... patterns (this case ... #Clinical #MRI ... #Brain #Diagnosis ... #Radiology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... basal ganglia, CNS ... Vascular Disease: Arterial ... (Clinical Dx). ... signs #symptoms #rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
cryoglobulins • Negative causes ... to medium-sized arteries ... Antiphospholipid syndrome ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
blisters containing pus ... Rheumatic pain Clinical ... Diagnosis: • A clinical ... Rule out other causes ... #Rheumatology #
Gout (Gouty Arthritis) - MSK Radiology Imaging Findings: • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Arthritis) - MSK Radiology ... Case description ... • PVNS/Giant Cell ... #Radiology #diagnosis ... #msk #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... Hypocomplementemia • Can cause ... salivary ducts Clinical ... Nephrogenic DI Hematologic ... #Rheumatology #
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