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diagnosis management differential blood clinical intravascular product reactions anemia antinxp2 antinxp2dm arterial cardiology coagulation dermatomyositis dic discoloration disseminated embolism eschar
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
: - Thrombocytopenia ... deficiencies - PNH ... Differential #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Thromboembolism (7%) • CNS ... involvement (2%) Cutaneous ... Treat primary cause ... Coagulation #diagnosis #causes ... treatment #management #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... microangiopathy: Thrombotic thrombocytopenic ... hemoglobinuria (PNH ... Extravascular #Causes ... differential #diagnosis #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
considered in all cases ... Heparin-induced thrombocytopenia ... coagulation and other causes ... - COVID-19 - PNH ... pathophysiology #hematology
If you haven't seen it, flecainide can cause significant yellowing of the skin and eyes.
flecainide can cause ... #flecainide #cutaneous ... sideeffects #clinical #photo ... #nails #cardiology ... #dermatology #discoloration
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... count ↑ PLT • ↑ PBS ... infiltrates (anemia, thrombocytopenia ... violaceous, nontender cutaneous ... #Leukemia #Hematology
Cutaneous Mucormycosis Eschar 30 M HIV cd4 10 VL 30k traumatic injury of arm few months ago
immunosuppressed pts ... mucor cases may ... therapy), some cases ... Mucormycosis #Eschar #dermatology ... skin #clinical #photo
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... severe thrombocytopenia ... TRALI): Leading cause ... include: fever, cutaneous ... diagnosis #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Causes purpura & ... severe thrombocytopenia ... TRALI): Leading cause ... include: fever, cutaneous ... diagnosis #management #hematology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
subcutaneous edema Pts ... in the neck Cutaneous ... Muscle atrophy may cause ... diagnosis #management #rheumatology ... #dermatology
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