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diagnosis differential neurology rheumatology syndrome dermatology algorithm clinical disease pediatrics ringenhancing antinxp2 antinxp2dm bee behcet behcets cardiology cardiomyopathy cerebritis childhood
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
CNS Ring-Enhancing ... + toxo IgG • CNS ... 30% present w/ CNS ... : • CNS Lymphoma ... @AnnKumfer #CNS
Algorithm for evaluating multiple ring-enhancing lesions in immunocompetent (HIV negative) #ringenhancing #lesions #cns #brain #diagnosis #differential #algorithm
ring-enhancing lesions ... ringenhancing #lesions ... #cns #brain #diagnosis ... differential #algorithm #causes ... #radiology #neurology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... autoantibodies that will cause ... thrombosis and/or blood-brain ... Erythematosus #SLE #CNS ... cerebritis #diagnosis #management
Childhood Immunization Schedule: Why we immunize • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
replicates within CNS ... induces vascular & CNS ... CNS and hematologic ... persists as skin lesions ... #Immunization #peds
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
basal ganglia, CNS ... meningitis), MCC CNS ... Arthritis, AS Treatment ... collaboration • CNS ... Syndrome #diagnosis #management
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Ulcers: • Treatment ... for refractory lesions ... or refractory lesions ... #management #pharmacology ... #rheumatology
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
Non-inflammatory Causes ... affecting the Brain ... nervous system (CNS ... diagnosis and treatment ... LHON) plus MRI lesions
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Thromboembolism (7%) • CNS ... + Bleeding Treatment ... Treat primary cause ... #treatment #management ... #hematology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... ruled out • Brain ... MRI: Check for brain ... Transverse Myelitis Treatment ... Myelitis #diagnosis #management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
parietal lobes of the brain ... showing cortical lesions ... the underlying cause ... • Treatment of ... Syndrome #diagnosis #management
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