22 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... autoantibodies that will cause ... Puncture, EEG Treatment ... #neurology #rheumatology
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Clarkson’s Disease - Capillary ... leak syndrome ... Relapsing-remitting course +++ Clinical ... Clarksons #Disease #Capillary ... #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... nervous system (CNS ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... + Bleeding Treatment ... Treat primary cause ... #treatment #management ... #hematology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
blisters containing pus ... Rheumatic pain Clinical ... Rule out other causes ... and lower jaw Treatment ... #Rheumatology #
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Arthritis) - MSK Radiology ... Case description ... • PVNS/Giant Cell ... #Radiology #diagnosis ... #msk #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... basal ganglia, CNS ... (Clinical Dx). ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
Leigh Syndrome 
History: 19-month-old girl with hypotonia, developmental 
delay, failure to thrive, and bilateral optic disc
Leigh Syndrome ... subthalamic nuclei, pons ... patterns (this case ... #Clinical #MRI ... Brain #Diagnosis #Radiology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Aplastic Anemia Clinical ... and petechiae Causes ... aplastic anemia Treatment ... Anemia #oncology #hematology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... salivary ducts Clinical ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment ... #Rheumatology #