20 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
other orthopedic complications ... • XR, MRI to ... dz difficult to see ... #differential #diagnosis ... #causes #hematology
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
, TIF1y, NXP2, Mi ... -2, SAE Anti-Synthetase ... Antibodies #MSAs #clinical ... #diagnosis #rheumatology ... #table
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... ) Clinical Manifestations ... autoantibodies that will cause ... Erythematosus #SLE ... #rheumatology #
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Case description ... prior signs or clinical ... • PVNS/Giant Cell ... #clinical #Radiology ... #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Discontinuation of causal ... #comparison #table ... #rheumatology # ... diagnosis #management
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... ancestry, LGE on MRI ... , LE edema • Minority ... Thromboembolic complications ... #management #cardiology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... • May involve PNS ... Thrombosis highest risk ... #Rheumatology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
factors: Critical ... without other cause ... Transfusion #Reactions #hematology ... #diagnosis #comparison ... #table
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... lymphocytic lymphoma (SLL ... Transformation: • Complication ... #Leukemia #Hematology ... #Oncology #Diagnosis
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
an underlying cause ... circulation = risk ... Better call hematology ... some time, let’s see ... Algorithm #workup #hematology