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diagnosis management myelodysplastic anthracycline cancer cardiomyopathy cardiotoxicity chemotherapy emergencies essential et hemeonc her2 leukemia myelodysplasia oncologic peripartum pharmacology syndrome syndromes
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... • Risks: infection ... transformation to acute ... only curative treatment ... #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
ALL (Acute Lymphoblastic ... -> AML: Blast crises ... Transformation: • Complication ... #Leukemia #Hematology ... #Oncology #Diagnosis
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... • Minority of Pts ... Thromboembolic complications ... diagnosis #management #cardiology ... #treatment
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
involve one, two, or all ... carries a variable risk ... and reducing the risk ... Syndromes #diagnosis #hematology ... #oncology
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Most cases are related ... , symptoms and complications ... generally requires all ... PV, MDS, CML) Treatment ... • Treatment algorithms
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
syndromes current treatment ... algorithm 2018. ... clonal evolution to acute ... of death from complications ... #algorithm #hematology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
syndrome): - Hematologic ... mg/dL or > 25 % rise ... Treat underlying cause ... interventional radiology ... AML (~20 %) and APL
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity Anthracyclines cause cardiomyopathy: ✖ Reduction in left ventricular ejection fraction
Anthracyclines cause ... LVEF) can occur acutely ... ) and initiate treatment ... Cardiotoxicity #cardiology ... #oncology #pharmacology
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