27 results
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... Most cases diagnosed ... prematurely • risk ... membrane into the CNS ... Phosphatase: • Other causes
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... count ↑ PLT • ↑ PBS ... Transformation: • Complication ... #Leukemia #Hematology ... #Oncology #Diagnosis
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
= nonspecific (nausea ... ) Differential Diagnosis ... Maternal Support - Critical ... Monitor and Treat Complications ... Liver #Pregnancy #hepatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
- Differential Diagnosis ... • Acquired Risk ... considered in all ... coagulation and other causes ... pathophysiology #hematology
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
• Sepsis Complications ... with an increased risk ... • Mitchell et al ... • Increased risk ... #cardiology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
immunophenotype Clinical ... thrombocytopenia Complications ... chemotherapy for low-risk ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Post-Transplantation Lymphoproliferative Disorders (PTLD)
Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
accounts for 21% of all ... immunocompetent population Risk ... symptoms, unexplained hematologic ... to 50% of PTLD cases ... Lymphoproliferative #Disorders #oncology
UCSF COVID-19 Adult Clinical Evaluation Guide - Updated April 10 2020

Clinical Presentation
• Fever: hospitalized pts but
: hospitalized pts ... in <35% • AST/ALT ... 7-28% -> Incr risk ... complications, ... Evaluation #Guide #Diagnosis
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... Differential Diagnosis ... Clinical • Under-recognized ... Thromboembolic complications ... #management #cardiology
USMLE Epidemiology and Biostatistics Summary
Meta-Analysis: pools data from several studies (greater power), limited by quality/bias of
individual studies Clinical ... Proves cause-effect ... diseases, describe clinical ... retrospective studies (pts ... #calculations #diagnosis