UCSF COVID-19 Adult Clinical Evaluation Guide - Updated April 10 2020 Clinical Presentation • Fever: hospitalized pts but only 50% on admit • Myalgias 10-50% • Respiratory: Cough 45-80%, dyspnea 20-50% • URI sx (HA, sore throat, rhinorrhea) <20% • GI: N/V, diarrhea <30%; can be only symptom 3-12% • Cardiac: multiple case reports of myocarditis • ENT: Taste or smell disorder in 34-89%, can occur before other symptoms appear • Eye: conjunctivitis in 32% (single study) Labs and Biomarkers • WBC usually normal or low (leukopenia 17-45%, leukocytosis lymphopenia in 33-85% • Platelets usually normal, can be low in <35% • AST/ALT incr in 4-35% • CRP incr in 61-86%, LDH incr in 27-75% • PCT: >0.5 in 5-10% (higher % if severe or ICU) • Troponin incr in 7-28% -> Incr risk complications, death • Higher inflammatory markers (CRP, D-dimer, IL-6, TNF-a) associated w severe disease, death - Dr. Jen Babik, UCSF COVID-19 ID Clinical Working Group #UCSF #COVID19 #Evaluation #Guide #Diagnosis #Algorithm #Protocol #SARSCoV2 #Coronavirus
