8 results
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
involvement: Intractable nausea ... pain • Extra-CNS ... complications ( ... positive NMO only): Myositis ... , Comorbid autoimmune
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... Parotid swelling CNS ... nervous system (CNS ... • 8%-27% for CNS ... effusion, INC risk
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... leukostasis syndrome: CNS ... Transformation: • Complication ... #Leukemia #Hematology ... #Oncology #Diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
disease • Non-autoimmune ... deficiencies • Autoimmune ... • May involve PNS ... and CNS • Headache ... Thrombosis highest risk
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... Risk Factors and ... • Minority of Pts ... Thromboembolic complications ... diagnosis #management #cardiology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
mg/dL or > 25 % rise ... Treat underlying cause ... interventional radiology ... ) - Symptoms: CNS ... ) - Symptoms: CNS
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis ... nucleotidase 1A (Anti cN ... aspiration > 50% of pts ... statins - probably caused ... #rheumatology #
Cryptococcal meningitis on T2 MRI
30 M from sub-Saharan Africa presents w/ progressive Headache x1 mo, +neck
low glucose) CNS ... Nausea & vomiting ... performed, relative risk ... have a higher risk ... Brain #clinical #radiology