15 results
Invasive Aspergillus (IA) - Diagnosis and Management
Aspergillus is ubiquitous in nature. Most invasive infections are caused
infections are caused ... complex Classic Risk ... HIV/AIDS, CGD) Clinical ... this morphology Treatment ... #fungal #infectiousdiseases
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
Fungal Biomarkers ... component of many fungi ... infection (IFI) in hematologic ... cut-offs defined in clinical ... useful in high risk
Candidemia Workup and Management - IDSA Guidelines
1) Antibiotics
 • Empiric: Echinocandins (e.g. micafungin) for most patients
Other hardware - Risk-Benefit ... or TEE unless clinical ... Consider: Spine, CNS ... #candidiasis #treatment ... #fungal #fungemia
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
immunophenotype Clinical ... thrombocytopenia Complications ... chemotherapy for low-risk ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... Clinical • Under-recognized ... Thromboembolic complications ... diagnosis #management #cardiology ... #treatment
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
> 4 days → add fungal ... syndrome): - Hematologic ... mg/dL or > 25 % rise ... Treat underlying cause ... interventional radiology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
MUCORMYCOSIS • Risk ... has five major clinical ... stain of clinical ... Encapsulated yeast • At risk ... ASPERGILLOSIS • Aspergillus
Empyema Necessitans (EN) on Chest Wall Physical Examination

Pulmonary teaching case: you are called to the bedside
: EN is a rare complication ... most common) - Fungus ... , Blastomyces, Aspergillus ... Fusobacterium Treatment ... #PhysicalExam #clinical
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
salivary ducts Clinical ... effusion, INC risk ... Nephrogenic DI Hematologic ... Malignancy Risk ... Adenocarcinoma Treatment
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma Risk ... Hodgkin Lymphoma - Clinical ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management