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diagnosis management anemia chronic cll lymphocytic mds myelodysplastic cardiomyopathy hemeonc myelodysplasia peripartum syndrome syndromes workup
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... old, ~10,000 new cases ... • Risks: infection ... transformation to acute leukemia ... #hematology #oncology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... neutropenic fever) Complications ... to MDS or acute leukemia ... • Associated PNH ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... -> AML: Blast crises ... count ↑ PLT • ↑ PBS ... Transformation: • Complication ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Pure red cell aplasia ... microglobulin Treatment ... • GI complications ... diagnosis #workup #oncology ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... virus (EBV) • Leukemia ... anemia Treatment ... #Anemia #oncology ... #hematology #diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic Leukemia ... • Most common leukemia ... thrombocytopenia Complications ... chemotherapy for low-risk ... #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
carries a variable risk ... • Anemia • Aplastic ... • Hairy Cell Leukemia ... Syndromes #diagnosis #hematology ... #oncology
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... • Minority of Pts ... Thromboembolic complications ... diagnosis #management #cardiology ... #treatment
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