20 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... thrombosis and/or blood-brain ... #neurology #rheumatology
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Clinical Findings Risk ... Apolipoprotein E4 allele Risk ... mutations - Down syndrome ... Signs / Symptoms / Complications ... AlzheimersDisease #Dementia #pathophysiology
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
CNS Ring-Enhancing ... Diagnosis- Compatible syndrome ... RingEnhancing #Lesions #Brain ... differential #diagnosis #causes ... #radiology #neurology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
• Acquired Risk ... • Nephrotic Syndrome ... coagulation and other causes ... Venous #Arterial #pathophysiology ... #hematology #differential
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
Electrolyte/fluid shifts caused ... changes and may cause ... severe clinical complications ... Risk Factors: ... Differential #Diagnosis #Pathophysiology
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
Diagnosis and Pathophysiology ... • Sepsis Complications ... • Increased risk ... Acute Coronary Syndrome ... #causes #cardiology
Leigh Syndrome 
History: 19-month-old girl with hypotonia, developmental 
delay, failure to thrive, and bilateral optic disc
Leigh Syndrome ... subthalamic nuclei, pons ... patterns (this case ... Clinical #MRI #Brain ... #Diagnosis #Radiology
Complications after Bariatric Surgery
Post Bariatric Intestinal Failure:
 • Severe protein malnutrition after bariatric surgery
 • More
Consider refeeding syndrome ... deficiencies) Dumping Syndrome ... Gastric bypass causes ... bariatric surgery are risk ... operative CCY risk
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
parietal lobes of the brain ... Etiology: • Pathophysiology ... Risk factors 3. ... the underlying cause ... with AEDs until cause
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Prevalence: 1-2 cases ... Pathophysiology ... gone awry in the brain ... positive in 2/3 of pts ... neurotransmitter in the brain