18 results
Alice in Wonderland Syndrome
What? Metamorphophsia - Distortions of the visual perceptions with changes in size (micro
in Wonderland Syndrome ... • CNS: parietal ... encephalitis) • Brain ... • Psychiatric disorders ... diagnosis #neurology #differential
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Kasabach-Merritt syndrome ... deficiencies - PNH ... Gardner-Diamond syndrome ... #Diagnosis #hematology
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
affecting the brain ... nervous system (CNS ... Inflammatory causes ... optica spectrum disorder ... #inflammatory #differential
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Headache, Movement disorders ... , Seizure disorders ... autoantibodies that will cause ... thrombosis and/or blood-brain
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
Diagnosis- Compatible syndrome ... RingEnhancing #Lesions #Brain ... #differential # ... diagnosis #causes ... #radiology #neurology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... hemoglobinuria (PNH ... lymphoproliferative disorders ... #differential # ... diagnosis #hematology
Leigh Syndrome 
History: 19-month-old girl with hypotonia, developmental 
delay, failure to thrive, and bilateral optic disc
Leigh Syndrome ... Mitochondrial disorder ... subthalamic nuclei, pons ... patterns (this case ... Clinical #MRI #Brain
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension - Workup and Differential ... An acute rise or ... apnea: CPAP, most pts ... Neurologic disorders ... #Differential #
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
• Acquired Risk ... • Nephrotic Syndrome ... coagulation and other causes ... pathophysiology #hematology ... #differential #
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
: • Valvular disorders ... with an increased risk ... • Increased risk ... Acute Coronary Syndrome ... #cardiology