20 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
of Systemic Lupus ... Erythematosus (SLE ... autoantibodies that will cause ... thrombosis and/or blood-brain ... #rheumatology #
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... l MD SOAP) - Risks ... test, ANA (e.g., SLE ... #Differential # ... #Workup #hematology
Alice in Wonderland Syndrome
What? Metamorphophsia - Distortions of the visual perceptions with changes in size (micro
CNS: parietal ... lobe • Retina • Systemic ... encephalitis) • Brain ... • Psychiatric disorders ... diagnosis #neurology #differential
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Splenomegaly - CTD (SLE ... deficiencies - PNH ... Associated - SLE ... Vasculopathy #Purpura #Differential
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
affecting the brain ... (CNS) involvement ... Inflammatory causes ... optica spectrum disorder ... #inflammatory #differential
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Nail Disorders secondary ... Abnormality • SLE ... #Secondary #dermatology ... #Differential # ... Diagnosis #Algorithm #causes
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Aortitis - Differential ... Arthritis (RA), Systemic ... erythematosus (SLE ... Cancer, Histiocytic disorders ... #Diagnosis #rheumatology
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
nodules, may also see ... RingEnhancing #Lesions #Brain ... #differential # ... diagnosis #causes ... #radiology #neurology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia Differential ... • May involve PNS ... vein thrombosis Hematologic ... Thrombosis highest risk
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
: • Valvular disorders ... Myeloproliferative disorders ... with an increased risk ... • Increased risk ... #cardiology