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diagnosis management dermatology lupus differential erythematosus skin systemic druginduced syndrome treatment activation algorithm antinxp2 antinxp2dm autoimmune canimorsus capnocytophaga cellulitis cerebritis
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... Positive in 60-80% of cases ... Management #Summary #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... Discontinuation of causal ... 40, F:M 9:1 • Clinical ... comparison #table #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Non-autoimmune rheumatologic ... • May involve PNS ... Thrombosis highest risk ... Erythematosus #Diagnosis #Rheumatology
Vibrio Vulnificus skin infection Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. Vibrio vulnificus part of
rapidly evolving rash ... necrotic ulcers Risk ... #cellulitis #dermatology ... #legs #clinical ... #photo
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... ) Clinical Manifestations ... autoantibodies that will cause ... Erythematosus #SLE ... #rheumatology #
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
nervous system (CNS ... Petechial or purpuric rash ... erythematosus [SLE ... Diagnosis #Management #Hematology ... #Rheumatology
Capnocytophaga Canimorsus Skin Rash 40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
dogs & latter can cause ... gram-negative bacillus cause ... patients at highest risk ... #dermatology #clinical ... #photo
Secondary Syphilis - Rash on Palms and Soles 41ys, seen in our ED b/c of 20
Secondary Syphilis - Rash ... present in 80% of cases ... Secondary #Syphilis #Rash ... #clinical #photo ... #physicalexam
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
an underlying cause ... circulation = risk ... Better call hematology ... some time, let’s see ... Algorithm #workup #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... salivary ducts Clinical ... effusion, INC risk ... Malignancy Risk ... Sjogrens #Syndrome #Rheumatology
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