11 results
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Causes of Extravascular ... • PCH • PNH ... immune-complex hemolytic anemia ... Diagnosis #Algorithm #Causes ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... hemoglobinuria (PNH ... #Causes #differential ... #diagnosis #hematology ... #anemia
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
Cardiovascular Causes ... - Water - Pus ... Barre - ALS - Transverse ... myelitis • Hematology ... : - Anemia
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... - Hemolytic anemia ... deficiencies - PNH ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Headaches • Pale skin ... and petechiae Causes ... #oncology #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Testosterone - Coumadin skin ... - Disseminated intravascular ... coagulation and other causes ... - COVID-19 - PNH ... pathophysiology #hematology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Alpha & Mu) Skin ... Amyloidosis (CVS+PNS ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... - infiltrates (anemia ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
Primary Dermatological Lesions
Primary lesions are physical changes in the skin considered to be caused directly by
considered to be caused ... features such as crusts ... flat macules of extravascular ... lesions that contain pus ... #Diagnosis #Dermatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... just beneath the skin ... Out Secondary Causes ... Syndromes #diagnosis #hematology ... #oncology