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differential management rheumatology infections infectiousdiseases abg acid acidbase alp aplastic base bloodgas coagulation dic disorders disseminated emergencies erythematosus gas hemeonc
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... leukostasis syndrome: CNS ... - infiltrates (anemia ... #Hematology #Oncology ... #Diagnosis
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
CNS Infection in ... HIV / AIDS - Differential ... CNS Opportunistic ... Infections: • Most CNS ... • CNS opportunistic
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Most cases diagnosed ... membrane into the CNS ... • Pernicious anemia ... respiratory failure • Neurologic ... Phosphatase: • Other causes
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
et diutinum Neurologic ... Scleromyxedema (CNS ... +PNS+GI+Endocrine ... (-) hemolytic anemia ... #Oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... immunodeficiency virus (HIV ... virus (EBV) • Leukemia ... #oncology #hematology ... #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
promyelocytic leukemia ... Thromboembolism (7%) • CNS ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
syndrome): - Hematologic ... Treat underlying cause ... ) - Symptoms: CNS ... ) - Symptoms: CNS ... #HemeOnc #Diagnosis
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... Myelitis Diagnosis ... • Infectious causes ... simplex virus, HIV ... #management #neurology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Parotid swelling CNS ... nervous system (CNS ... peripheral neuropathy, transverse ... • 8%-27% for CNS ... Nephrogenic DI Hematologic
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
- Differential Diagnosis ... Lymphadenopathy, CNS ... ), anemia, arthralgia ... #AIDS #pulmonary ... #differential #diagnosis
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