13 results
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
CNS Infection in ... HIV / AIDS - Differential ... CNS Opportunistic ... Infections: • Most CNS ... Demyelinating disease caused
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Systemic Lupus Erythematosus ... autoantibodies that will cause ... #SLE #CNS #neurology ... #rheumatology #
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
et diutinum Neurologic ... Scleromyxedema (CNS ... +PNS+GI+Endocrine ... (-) hemolytic anemia ... #Oncology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
• May involve PNS ... and CNS • Headache ... neuropathy • Transverse ... lymphopenia, low PLT • Anemia ... #Diagnosis #Rheumatology
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
Many others • Transverse ... pain • Extra-CNS ... Systemic lupus erythematosus ... Manifestations #diagnosis ... #neurology #symptoms
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... Myelitis Diagnosis ... • Infectious causes ... simplex virus, HIV ... #management #neurology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... leukostasis syndrome: CNS ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
papules, pustules, erythematous ... Lymphadenopathy, CNS ... factor • May cause ... ), anemia, arthralgia ... #AIDS #pulmonary
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... membrane into the CNS ... • Pernicious anemia ... respiratory failure • Neurologic ... Phosphatase: • Other causes
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... Parotid swelling CNS ... nervous system (CNS ... peripheral neuropathy, transverse ... • 8%-27% for CNS