21 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
(MD) - Diagnosis ... old, ~10,000 new cases ... cytopenias (usually anemia ... #MDS #Diagnosis ... #hematology #oncology
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
- Water - Pus ... Hepatopulmonary syndrome ... Barre - ALS - Transverse ... myelitis • Hematology ... : - Anemia
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Headaches • Pale skin ... and petechiae Causes ... (MDS) (normal or ... #oncology #hematology ... #diagnosis #management
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... purple, hemorrhagic skin ... - Hemolytic anemia ... deficiencies - PNH ... #hematology #rheumatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
et diutinum Neurologic ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... that are caused ... Out Secondary Causes ... #diagnosis #hematology ... #oncology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... autoantibodies that will cause ... Maheswaranathan, MD ... #neurology #rheumatology ... #management #treatment
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
response to local skin ... injury) • Neurologic ... test (this is a skin ... #diagnosis #management ... signs #symptoms #rheumatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
blisters containing pus ... • A clinical diagnosis ... Rule out other causes ... diagnosis #management ... #Dermatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... nervous system (CNS ... with leukopenia, anemia ... #Diagnosis #Management ... #Hematology #Rheumatology