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diagnosis rheumatology differential syndrome activation antinxp2 antinxp2dm aplastic dermatomyositis dyspnea hemeonc hemophagocytic hiv hlh infections infectiousdiseases lung lymphohistiocytosis macrophage sapho
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
- Water - Pus ... Barre - ALS - Transverse ... myelitis • Hematology ... : - Anemia • ... #pulmonary
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Illness Script Signs ... Can progress to MDS ... • Associated PNH ... #diagnosis #management ... #treatment #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
juvenile idiopathic arthritis ... nervous system (CNS ... with leukopenia, anemia ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... develop in pts ... tract, and often causes ... arthritis. ... Differential #Diagnosis #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
peripheral neuropathy, transverse ... , INC risk PE, Pulmonary ... Nephrogenic DI Hematologic ... Arthralgia and Arthritis ... #Diagnosis #Management
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
blisters containing pus ... nonerosive inflammatory arthritis ... Rule out other causes ... #diagnosis #management ... #Dermatology
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
• CT: Halo sign ... Lymphadenopathy, CNS ... ), anemia, arthralgia ... Infections #HIV #AIDS ... #pulmonary #differential
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
subcutaneous edema Pts ... chest (in a V-sign ... cause weakness ... Dermatomyositis #diagnosis #management ... dermatology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome caused ... (often termed MAS-HLH ... Presentation • Common Signs ... - Cytopenias (anemia ... #Hematology #HemeOnc
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