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diagnosis rheumatology differential management erythematosus lupus systemic ra syndrome vasculitis aids algorithm arteritis autoantibodies autoimmune behcet chronic classification disease dyspnea
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
- Water - Pus ... Barre - ALS - Transverse ... myelitis • Hematology ... : - Anemia • ... #pulmonary
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Neoplastic / Hematologic ... • Anemia • ... • Rheumatoid Arthritis ... • SLE • Polymyalgia ... Chronic Obstructive Pulmonary
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
of hip (rare), Arthritis ... ) Blood (75%): Anemia ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
symptoms (headache ... Oral aphthae : SLE ... : SLE, Reactive ... diagnosis #management #signs ... #symptoms #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Manifestations: - Arthritis ... - Hemolytic anemia ... Lupusreference #SLE ... autoantibodies #signs ... #symptoms #mimickers
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
• May involve PNS ... neuropathy • Transverse ... vein thrombosis Hematologic ... lymphopenia, low PLT • Anemia ... Induced Lupus: • Symptoms
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
Rheumatoid Arthritis ... - Signs and Symptoms ... Scleromalacia perforans • Pulmonary ... Hematological: Anemia ... #RA #Signs #Symptoms
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
Rheumatoid arthritis ... reticularis Blood: Anemia ... inflammation tends to cause ... pathophysiology #signs ... #symptoms #diagnosis
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... chronic onset of symptoms ... -> AML: Blast crises ... - infiltrates (anemia ... #Leukemia #Hematology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
noninflammatory Signs ... constitutional symptoms ... weeks) Can Be Caused ... • SLE • Psoriatic ... Symmetrical: • RA • SLE
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