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diagnosis differential management rheumatology activation anemia arterial dermatologic dress dyspnea embolism extravascular gpa granulomatosis hemolysis hemolytic leukemia macrophage mas pathophysiology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... ) - HELLP syndrome ... Hemolytic uremic syndrome ... hemoglobinuria (PNH ... #diagnosis #hematology
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
Cardiovascular Causes ... - Water - Pus ... Hepatopulmonary syndrome ... Barre - ALS - Transverse ... myelitis • Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Maculopapular rash ... • Goodpasture syndrome ... Polyangiitis #GPA #dermatology ... #rash #diagnosis
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
• Nephrotic Syndrome ... - Disseminated intravascular ... coagulation and other causes ... - COVID-19 - PNH ... pathophysiology #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
and generalized lymphadenopathy ... nervous system (CNS ... Petechial or purpuric rash ... Diagnosis #Management #Hematology ... #Rheumatology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
- Rash: multiple ... Causes: - Idiopathic ... , breast CA - Hematologic ... #diagnosis #dermatology ... #oncology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
extensive skin rash ... organ involvement, lymphadenopathy ... Edema in 70% of cases ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis
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