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diagnosis differential anemia druginduced extravascular hemolytic intravascular sle comparison complications erythematosus manifestations polycythemia sicklecell sjogrens summary syndrome systemic table testing
Algorithm for the Evaluation and Management of Sickle Cell Crises Clinical Manifestations and Management #Diagnosis #Management #Hematology #SickleCell
Algorithm for the ... of Sickle Cell Crises ... #Hematology #SickleCell ... Manifestations #Workup ... #Algorithm #Ddxof
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Differential Diagnosis Algorithm ... • PCH • PNH ... • MAHA (TTP, DIC ... #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... hemoglobinuria (PNH ... usually IgG) (e.g. lupus ... Extravascular #Causes ... differential #diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... platelet decrease - PNH ... thrombocytopenia - DIC ... Differential #Diagnosis #Algorithm ... #workup #hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... Discontinuation of causal ... • Immunologic Workup ... comparison #table #rheumatology ... #diagnosis #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... of SLE versus DIL ... • Immunologic Workup ... Positive in 60-80% of cases ... #Summary #rheumatology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... • Immunologic Workup ... Discontinuation of causal ... #DIL #rheumatology ... diagnosis #treatment #management
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Differential Diagnosis Algorithm ... an underlying cause ... Better call hematology ... JAK2 V617F) and MPNs ... #workup #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... peripheral neuropathy, transverse ... Hematologic: ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
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