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diagnosis differential anemia bruising cryoglobulinemia cryoglobulins dyspnea erythematosus hemolytic lupus management mcv polycythemia pulmonary sjogrens sle sob syndrome systemic testing
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
Cardiovascular Causes ... - Water - Pus ... Pulmonary HTN - Vasculitis ... Barre - ALS - Transverse ... myelitis • Hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Differential Diagnosis Algorithm ... • Steroids • Vasculitis ... Coagulation #Bleeding ... #Causes #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Differential Diagnosis Algorithm ... 80-100 fL) • Bleeding ... #Anemia #MCV #Classification ... #Causes #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... platelet decrease - PNH ... cardiac valve, vasculitis ... Differential #Diagnosis #Algorithm ... #workup #hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
immune system, leading ... • They can cause ... Cryoglobulins Cause ... diagnosis #types #classification ... #rheumatology #
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Differential Diagnosis Algorithm ... : neuro, heme (bleeding ... Better call hematology ... JAK2 V617F) and MPNs ... #workup #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... Non-autoimmune rheumatologic ... • May involve PNS ... neuropathy • Transverse ... Erythematosus #Diagnosis #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... peripheral neuropathy, transverse ... ) • Cutaneous vasculitis ... Nephrogenic DI Hematologic ... Sjogrens #Syndrome #Rheumatology
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