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diagnosis rheumatology differential management dermatology pulmonary syndromes acr2021 algorithm ana antibodies antibody antineutrophil antinuclear bee classification diseases dyspnea egpa eosinophilic
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... Parasites Drugs: - DRESS ... Asthma Tugs (vasculitis ... Hypereosinophilic Syndrome ... #hematology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
• Sjögren syndrome ... Vasculitis: • ... + 60% • Eosinophilic ... Renal-limited vasculitis ... antibodies #diagnosis #rheumatology
Eosinophilic Granulomatosis with Polyangiitis (EGPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021 Guidelines • Active
Eosinophilic Granulomatosis ... Polyangiitis (EGPA) - ANCA ... Vasculitis Management ... alone in select pts ... #Treatment #ACR2021
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
• EGPA: - Eosinophilia ... tract, and often causes ... Vasculitis: + MPO-ANCA ... : • Behçet Syndrome ... • Cogan Syndrome
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
- Water - Pus ... Pulmonary HTN - Vasculitis ... Hepatopulmonary syndrome ... Barre - ALS - Transverse ... myelitis • Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Kasabach-Merritt syndrome ... deficiencies - PNH ... Gardner-Diamond syndrome ... Cryoglobulinemia (MIXED) • ANCA ... Differential #Diagnosis #hematology
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
nervous system (CNS ... diagnosis and treatment ... Inflammatory causes ... spectrum disorder • ANCA-associated ... vasculitides •
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
progressive) EGPA (Eosinophilic ... Polyangiitis): • Eosinophilia ... tract, and often causes ... • Behcet syndrome ... • Cogan syndrome
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Systemic Symptoms (DRESS ... Edema in 70% of cases ... disease: symptomatic treatment ... SinaiBmoreIMRes #DRESS ... #Syndrome #dermatology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Summary Autoimmune ANCA ... vasculitis (AAV ... Auto-antibodies: ANCA ... Goodpasture's cause ... diagnosis #management #treatment
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