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causes potassium hyperkalemia acidosis algorithm aniongap apml differentiation framework hematology hypophosphatemia low medications metabolic nongap pharmacology phosphate renal rhabdomyolysis table
Causes of Hypokalemia Transcellular Shifts: - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
plasma insulin (treatment ... , Osmotic diuresis ... Hypomagnesemia, Acute ... #Causes #differential ... #diagnosis #nephrology
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
• Diagnosis of ... irrigation • Management ... ; High-Ceiling Diuretics ... Tolvaptan) • Treatment ... #Diuresis #Nephrology
Workup for Hypophosphatemia - Differential Diagnosis Framework Rule out spurious hypophosphatemia: paraproteinemia, acute leukemia Measure Urine Fractional Excretion
Diagnosis Framework ... Urine Fractional Excretion ... , Tumor genesis ... Inh., Osmotic diuresis ... Workup #phosphate #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... • K sparing diuretics ... lysis syndrome ... Impaired Renal Excretion ... #nephrology
Hypokalemia Evaluation Algorithm Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
urinary losses: • High ... Renin secreting tumor ... Alkalosis: Emesis, Diuretics ... #differential # ... potassium #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... • K sparing diuretics ... lysis syndrome ... Impaired Renal Excretion ... #nephrology
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis Causes of High-anion Gap Acidosis: • Lactic acidosis
Renal failure (acute ... Potassium-sparing diuretics ... ketosis with ketone excretion ... #diagnosis #causes ... #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Diagnosis Framework ... and Management ... Loop diuretics for ... #Diagnosis #Management ... #nephrology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
• Attempt if high ... initiation • Differential ... Supportive Care: Diuresis ... #management #hematology ... #oncology
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