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Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
New Potassium-Binding ... #Potassium #Binding ... #KBinders #Kayexelate ... #Comparison #Table ... Pharmacology #Patiromer #HyperKalemia
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... nonspecifically binds ... aspiration #Potassium #Binding ... #pharmacology #table ... #comparison #binders
Phosphate binders - quick reference chart of maximum daily dose. Most patients with CKD will require
Phosphate binders ... require phosphate binding ... since they are not able ... aluminum-based phosphate binder ... restricted due to hypercalcemia
What is the difference between ischemic colitis and mesenteric ischemia?
A common misnomer. Mesenteric ischemia and ischemic
What is the difference ... initial treatment algorithms ... mesentericischemia #comparison ... #differences #diagnosis ... #table
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
Hyperkalemia - Management ... Algorithm • IV ... • Consider K+ binder ... waves, Prolonged PR ... , asystole #hyperkalemia
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... Management of Hyperkalemia ... #Management #Hyperkalemia ... #pharmacology #table ... #comparison #nephrology
Characteristics of Commonly Used Phosphate Binders 
Aluminum 
 - Potent and effective 
 - Useful for
Used Phosphate Binders ... Lower risk of hypercalcemia ... range - Lack of hypercalcemia ... #Phosphate #Binders ... #Table #Comparison
Table 22 provides the characteristics of various phosphate-binding agents.
#Pharmacology #Nephrology #Phosphate #Phosphorus #Binders #Comparison #Table #Disadvantages
Table 22 provides ... various phosphate-binding ... Phosphate #Phosphorus #Binders ... #Comparison #Table
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... , ST depress, ↑PR ... Elimination (see Table ... Treatments: • K-Binding ... SPS (15-60g PO/PR