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diagnosis hematology differential anemia algorithm management microscopy causes clinical smear atlas hematuria morphology path hemolytic hepatology macrocytic macrocytosis microbiology pathophysiology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Diagnosis Algorithm Blood ... Decreased RBC ... Infiltration Increased RBC ... Thalassemia • RBC ... Disorder • RBC
ABO Blood Types and Transfusion Compatibility Table A Blood Type: • RBC Antigens: A • Antibodies: Anti-B
ABO Blood Types ... Type: • RBC Antigens ... Type: • RBC Antigens ... Type: • RBC Antigens ... Type: • RBC Antigens
Blood Product Components, Contents, Volume and Shelf Life Whole blood (autologous or directed donations) - RBC and
Blood Product Components ... directed donations) - RBC ... Hct of 70-80% - RBC ... plasma, a few RBC ... ofplasma, a few RBC
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... RBC) Morphology ... Microcytic RBC: ... disease, McLeod blood ... Bite Cell RBC: G6PD
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases Acanthocyte (spur cell), Basophilic stippling, Bite cell,
Pathologic Red Blood ... Cell (RBC) Morphologies ... cell, Other RBC ... Howell-Jolly bodies #RBC
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
== Decreased RBC ... Glucose Content • RBC ... Reduction == Increase RBC ... turnover • Acute blood ... Dilutional Effect • RBC
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
individual’s red blood ... cells (RBCs or ... serum due to the RBCs ... Clinical #Path #Blood ... Smear #Microscopy #RBC
Plasmodium falciparum life cycle 1: Mosquito bite, transmission of sporozoite 2: Liver, Asexual replication. 1 sporozoite → 10-30,000
merozoites 3: Blood ... Merozoites infect RBC ... RBC ruptures releasing ... Merozoites infect other RBCs
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
individual’s red blood ... cells (RBCs or ... serum due to the RBCs ... Clinical #Path #Blood ... Smear #Microscopy #RBC
Red Blood Cell Morphology Atlas Size variation, Hemoglobin distribution, Hypochromia, Shape variation, Inclusions, Red
Red Blood Cell Morphology ... Diagnosis #Path #Blood ... #Smear #RBC #Morphology
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