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diagnosis hematology anemia differential microscopy algorithm clinical management causes workup atlas morphology path hemolytic macrocytic macrocytosis microbiology peripheral transfusion autoagglutination
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Diagnosis Algorithm Blood ... Decreased RBC ... Infiltration Increased RBC ... Thalassemia • RBC ... Disorder • RBC
Plasmodium Falciparum Blood Smear. Key features suggesting Plasmodium falciparum: - extreme parasitemia - normocytic RBCs (vivax, ovale prefer big
Plasmodium Falciparum Blood ... Smear. ... parasitemia - normocytic RBCs ... multiples per RBC ... #Smear.
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
2) External (RBC ... 3) Internal (RBC ... - Peripheral Blood ... Smear ↑ abnormal ... Differential #Diagnosis #hematology
Red Blood Cell Morphology Atlas Size variation, Hemoglobin distribution, Hypochromia, Shape variation, Inclusions, Red
Red Blood Cell Morphology ... Diagnosis #Path #Blood ... #Smear #RBC #Morphology
ABO Blood Types and Transfusion Compatibility Table A Blood Type: • RBC Antigens: A • Antibodies: Anti-B
Type: • RBC Antigens ... Type: • RBC Antigens ... Type: • RBC Antigens ... Type: • RBC Antigens ... Compatibility #Table #hematology
Babesia spp. on Peripheral Blood Smear Microscopy - Multiple small parasites per RBC - "maltese cross"
on Peripheral Blood ... Smear Microscopy ... parasites per RBC ... microbiology #peripheral #blood ... #smear
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
individual’s red blood ... cells (RBCs or ... Clinical #Path #Blood ... #Smear #Microscopy ... #RBC #Autoagglutination
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
individual’s red blood ... cells (RBCs or ... Clinical #Path #Blood ... #Smear #Microscopy ... #RBC #Autoagglutination
Blood Product Components, Contents, Volume and Shelf Life Whole blood (autologous or directed donations) - RBC and
directed donations) - RBC ... Hct of 70-80% - RBC ... plasma, a few RBC ... ofplasma, a few RBC ... Contents #Volume #Hematology
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Abnormal peripheral smear ... • Extrinsic RBC ... • Intrinsic RBC ... Diagnosis #Algorithm #hematology
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