20 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Triggering factor (infection ... : • Infections ... Still disease, Infection ... Etiological+++: Anti-infectious ... treatment #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
presentation, and most ... can mimic common infections ... Treatment: • Infection ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Post-Transplantation Lymphoproliferative Disorders (PTLD)
Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
Post-Transplantation ... , intensity of induction ... symptoms, unexplained hematologic ... #Post #Transplantation ... oncology #diagnosis #management
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
hypogammaglobulinemia -> increased infection ... history of recurrent infections ... disease • Infectious ... community-acquired infections ... hypogammaglobulinemia #immunology #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lymphohistiocytosis (HLH ... SLE], AOSD) • Infection ... hypersensitivity syndromes • HLH ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Framework Non-Infectious ... , Sarcoidosis, HLA-B27 ... rare), Idiopathic Infectious ... Aortitis: • Most ... Differential #Diagnosis #rheumatology
Kawasaki Disease (KD) - Diagnosis and Management Summary

Kawasaki Disease (KD) is the most common vasculitis of
Diagnosis and Management ... Disease (KD) is the most ... cæxist with other infections ... Bilateral conjunctival injection ... KD #vasculitis #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment
Primary HLH:
 - HLH-94 Protocol
    • Dexamethasone
Treatment Primary HLH ... : - HLH-94 Protocol ... associated with infection ... #Treatment #management ... #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
distribution curve - most ... History of EBV infection ... (NSHL) - (most ... classification #hematology ... #oncology #management
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
deficiency) • Post ... Infection - Infection ... likely to cause infections ... Transfusion #diagnosis #management ... #hematology #reactions