46 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Peripheral Smear ... Vasculitides, IBD, Celiac disease ... Kawasaki, Nephrotic syndrome ... pancreatitis, Post-surgical ... Others: Asplenia/post-splenectomy
Adjuvant therapies in critical care: steroids to treat infectious diseases
 - Severe Community Acquired Pneumonia
steroids to treat infectious ... diseases - Severe ... respiratory distress syndrome ... Corticosteroids #Adjuvant #InfectiousDiseases ... #Management #Treatment
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
other cancers: Most ... and M panel Management ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... #diagnosis #management
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Drug-associated, PCH, Evans Syndrome ... , Drugs, Liver Disease ... Internal (RBC) - Infections ... Electrolytes: Wilson's disease ... Peripheral Blood Smear
Causes of Pleural Effusion - Differential Diagnosis Algorithm
Transudate - Hydrostatic
 • Congestive heart failure
 • Constrictive
Urinothorax Exudate - Infectious ... Collagen vascular disease ... Gastrointestinal disease ... • Post-CABG ... Diagnosis #Algorithm #Hepatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Cold-induced symptoms - most ... IgM) • Blood smear ... Polyclonal IgM post ... hemolytic #anemia #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Diagnosis and Management ... thrombocythemia), Autoimmune disease ... disorders • Shear ... #treatment #hematology
Causes of Biliary Dilatation - Differential Diagnosis
 • Physiological: ↑ Age, Cholecystectomy, Opioid dependence, Post-sphincterotomy
 •
cyst, Caroli's disease ... sludge), Mirizzi's syndrome ... secondary SC), IgG4, Post-op ... stenosis, Parasitic infection ... differential #diagnosis #hepatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... Hemolytic uremic syndrome ... Mycoplasma pneumoniae infection ... antibiotics are the most ... spherocytosis) • Infections
Problem Representation - Approach to the Infectious Disease Patient

Who: Patient age and host/risk factors (such as
Approach to the Infectious ... Disease Patient ... Patient age and host ... define the clinical syndrome ... febrilepodcast@gmail.com #InfectiousDiseases