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differential treatment causes hematology microbiology oncology algorithm classification rheumatology neurology dermatology disease workup chagas checklist clinical fever gastroenterology hiv leukemia
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
peripheral blood smear ... Malaise, bleeding, infections ... pain, bleeding, infections ... bruising, bleeding, infection ... Hematology #Oncology #Diagnosis
CENTRAL FACIAL / NASAL LESIONS Bacteria: • Leprosy (saddle nose deformity) • Tuberculosis (lupus vulgaris)l • Endemic
Endemic treponemal infection ... Invasive mold infection ... Trigeminal trophic syndrome ... Central #Lesions #infections ... #diagnosis #infectiousdiseases
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
- Due to Viral infection ... Polyclonal - Viral Infection ... Check For: • Infections ... Polyclonal IgM post ... infectious setting
Disseminated Gonococcal Infection - Diagnosis and Management Summary Bacteremic spread of the Gram-negative diplococci Neisseria gonorrhoeae. History
Disseminated Gonococcal Infection ... Management Summary ... symptomatic genital infection ... Disseminated #Gonococcal #Infection ... #InfectiousDiseases
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Peripheral Smear ... Kawasaki, Nephrotic syndrome ... TPO, TPO-RA • Infections ... : Chronic infections ... bacterial and viral infections
Invasive Aspergillus (IA) - Diagnosis and Management Aspergillus is ubiquitous in nature. Most invasive infections are caused
Most invasive infections ... Rhinosinusitis, CNS infection ... , Disseminated infection ... systemic vori Infectious ... #fungal #infectiousdiseases
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Triggering factor (infection ... Acquired HLH: • Infections ... Still disease, Infection ... Etiological+++: Anti-infectious ... #management #treatment
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
: • Most common ... weeks without infection ... Diagnosis: • ... • Peripheral smear ... • Richter’s Syndrome
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... ) - HELLP syndrome ... ) (e.g. lupus, CLL ... Mycoplasma pneumoniae infection ... spherocytosis) • Infections
Blurry vision in a patient with HIV/AIDS Anterior Segment: • Herpes zoster ophthalmicus • Keratitis (HSV, Staph,
Cocci*, Toxo*, non-infectious ... • Choroidal infections ... syphilis) *Most ... vision #HIVAIDS #InfectiousDiseases ... #Differential #Diagnosis
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