22 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Autoimmune diseases ... chemotherapy, anti-CD20 (PTLD ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Peripheral Smear ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... pancreatitis, Post-surgical ... Others: Asplenia/post-splenectomy
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
presentation, and most ... age, however the disease ... : • Infection ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
IDSA Recommendations for Preventing and Treating Chagas Disease (American Trypanosomiasis) in HIV-AIDS
Preventing Clinical Disease
Indication:  Individuals
IDSA Recommendations ... (American Trypanosomiasis ... #Trypanosomiasis ... #Treatment #management ... opportunistic #infections
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary
Chagas disease (American trypanosomiasis) is an infectious
Diagnosis and Management ... ) is an infectious ... family Route of infections ... positive serology, smear ... thick peripheral smears
Chagas Disease (American trypanosomiasis) - Diagnosis and Management Summary
Acute Chagas Disease (8-12 weeks):
 • Mild: Malaise,
American trypanosomiasis ... Diagnosis and Management ... detectable by blood smears ... • Treatment: ... useful for chronic infection
Hemophagocytic Lymphohistiocytosis (HLH) Treatment
Primary HLH:
 - HLH-94 Protocol
    • Dexamethasone
associated with infection ... or autoimmune disease ... for refractory disease ... #Treatment #management ... #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lymphohistiocytosis (HLH ... SLE], AOSD) • Infection ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
• Peripheral smear ... Complications: 1) Infection ... chemotherapy for low-risk disease ... Leukemia #oncology #hematology ... hemeonc #diagnosis #management
Kawasaki Disease (KD) - Diagnosis and Management Summary

Kawasaki Disease (KD) is the most common vasculitis of
Kawasaki Disease ... (KD) is the most ... cæxist with other infections ... KD #vasculitis #rheumatology ... #treatment