13 results
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Diagnosis and Management ... Diagnosis: • Clinical ... Bayesian approach for post-test ... A/C if clinical ... #Treatment #Hematology
Our approach to the diagnosis and initial management of patients with suspected HIT. Our approach is
diagnosis and initial management ... based primarily on clinical ... and to adjust treatment ... #Hematology #HIT ... #Heparin #Induced
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... +++ (Plt, Hb), Hepatic ... chemotherapy, anti-CD20 (PTLD ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... splenomegaly • Hepatic ... Disease #diagnosis #management ... #treatment #rheumatology
Susac Syndrome - Clinical Triad
 - Central nervous system dysfunction
 - Branch retinal artery occlusion
 -
Susac Syndrome - Clinical ... Sensorineural hearing ... arterioles - Treatment ... Triad #Diagnosis #Management ... #Rheumatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... + Bleeding Treatment ... 100mg/dL) - Heparin ... diagnosis #causes #treatment ... #management #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Overview: • Most ... immunophenotype Clinical ... transformation) Treatment ... Leukemia #oncology #hematology ... hemeonc #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... presentation, and most ... • Bicytopenia Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... • Synovitis: most ... and lower jaw Treatment ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
years of age • Most ... association • M > F Clinical ... Arthritis, AS Treatment ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology