9 results
Post-Transplantation Lymphoproliferative Disorders (PTLD)
Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
Post-Transplantation ... ) Definition: Lymphoid ... symptoms, unexplained hematologic ... Lymphoproliferative #Disorders #oncology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... lymphoma, B-cell ... lymphoma (DLBCL ... chemotherapy, anti-CD20 (PTLD ... #management #treatment
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
: • Most common ... Lymphadenopathy • Fevers ... Diagnosis: • ... #workup #oncology ... #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... • Dyspnea • Fever ... Workup: • Full ... #hematology #oncology ... #management
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
presentation, and most ... following: • Fever ... Low or absent NK cell ... #management #treatment ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
) B symptoms → fevers ... lymphoma (Richter ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Internal organs Most ... general feeling of ill ... (malignancy), lymphoma ... , breast CA - Hematologic ... #dermatology #oncology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
full infectious work-up ... days → add fungal work-up ... syndrome): - Hematologic ... ± tocilizumab; call ... #HemeOnc #Diagnosis
Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40
Males • Affects all ... Nonspecific symptoms: Fever ... Viral infection • Lymphoma ... /EGPA • RA Diagnosis ... #diagnosis #management