15 results
Post-Transplantation Lymphoproliferative Disorders (PTLD)
Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
Post-Transplantation ... symptoms, unexplained hematologic ... #Post #Transplantation ... Lymphoproliferative #Disorders #oncology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... Unknown cause Treatment ... chemotherapy, anti-CD20 (PTLD ... #management #treatment ... #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
presentation, and most ... following: • Fever ... Low or absent NK cell ... #management #treatment ... #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
: • Most common ... Lymphadenopathy • Fevers ... microglobulin Treatment ... #workup #oncology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Overview: • Most ... ) B symptoms → fevers ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Kawasaki Disease (KD) - Diagnosis and Management Summary

Kawasaki Disease (KD) is the most common vasculitis of
Disease (KD) is the most ... Presentation: • Fever ... Criteria - Fever ... #pediatrics #diagnossi ... #management #treatment
Septic Arthritis - Diagnosis and Management Summary
Clinical Exam: hot, swollen, pain with passive AND active ROM
and Management ... active ROM +/- fever ... viral arthritis Workup ... Treatment: admission ... 90% sensitive in pediatrics
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... Hodgkin Lymphoma Workup ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... search for and treatment ... Fever b. ... Treatment Approach ... #Management #Hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... • Induce blast cell ... Subacute-Acute: • Common: fever ... #management #hematology ... #oncology