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differential algorithm oncology management anemia hemophagocytic hepatology hiv hlh injury leukemia liver lymphohistiocytosis agglutinin aids aplastic chronic classification cns cold
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CLL Acute leukemias ... ALL (Acute Lymphoblastic ... - Blood & BM • ... #Leukemia #Hematology ... #Oncology #Diagnosis
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... - Differential Diagnosis ... C, A, E, B, D, EBV ... Disease, Sickle Cell ... #Causes #Acute
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Diagnosis: • ... surface molecules: CD5 ... ’s lymphoma or acute ... #workup #oncology ... #hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Infectious • EBV ... Fatigue • Acute ... Reed-Sternberg Cells ... #Hematology #Oncology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... When do you do a BM ... #Causes #Workup ... #hematology
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia DIAGNOSTIC CRITERIA FOR ICL • Persistent CD4 T-cell lymphopenia •
Lymphocytopenia DIAGNOSTIC ... 300 cells/mL or ... EBV. CMV. ... #hematology #Differential ... #Causes #lymphocytopenia
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... T cells (IFN-y) ... Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... treatment #summary #rheumatology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... High in acute blood ... in bone marrow (BM ... under 2%, then BM ... #Workup #Hematology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
- Differential Diagnosis ... than 200 cells ... per μL • Diagnosis ... Demyelinating disease caused ... effect/Edema • EBV
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Toxic injury to BM ... and petechiae Causes ... Parvovirus B19 - EBV ... Anemia #oncology #hematology ... #diagnosis #management
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