20 results
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
- Differential Diagnosis ... , HCV, HEV, EBV, ... Metabolic: Wilson Disease ... obstruction syndrome • Autoimmune ... #causes #hepatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
., HIV), EBV infection ... , Autoimmune diseases ... Pylori) - Autoimmune ... : GI, neuro, cutaneous ... Differential Diagnosis
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
- Differential Diagnosis ... C, A, E, B, D, EBV ... , CMV, HSV • Toxic ... Other: NAFLD, Autoimmune ... #Differential #Diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... EBV, HSV, CMV, ... • Autoimmune: ... Autoimmune hepatitis ... #differential #diagnosis
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
common in SLE, autoimmune ... biliary cirrhosis (PBC ... Anti-GBM - Goodpasture's ... #diagnosis #table ... #rheumatology #
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... Risks factor for HIV ... When do you do a BM ... #hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... EBV, CMV), Alcohol-related ... liver disease, ... steatosis • Autoimmune ... #Algorithm #hepatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral infection, autoimmune ... - Mycoplasma, EBV ... , HIV, rubella legionella ... CLL (older) • Autoimmune ... hemolytic #anemia #hematology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Hepatitis A/B/C/D/E, EBV ... , CMV, HSV, VZV ... Other: NAFLD, Autoimmune ... HELLP, Celiac disease ... #hepatology #algorithm
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Infections+++: Virus (EBV ... solid cancers • Autoimmune ... diseases: SLE++ ... Adult-onset Still disease ... biologics (CMV +++, EBV