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diagnosis differential oncology algorithm causes management agglutinin anemia cd4 classification cold comparison diffuse disease gap globulin hemolytic hemophagocytic hepatitis hlh
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Hodgkin's Lymphoma ... Hodgkin's Lymphoma ... Immunosuppression (e.g., HIV), EBV ... , Hodgkin Lymphomas ... #differential #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin's Lymphoma ... Hodgkin Lymphoma ... • Hodgkin's lymphoma ... • History of EBV ... classification #hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Infectious • EBV ... Cells on Biopsy ... • Hodgkin's ... Lymphoma #Diffuse ... Algorithm #Causes #Hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Infections+++: Virus (EBV ... Hemopathies+++: Hodgkin ... , T-cell lymphoma ... , B-cell lymphoma ... biologics (CMV +++, EBV
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
HBV, HCV, HEV, EBV ... , PSC, IgG4, HLH ... cell lung CA, lymphoma ... intestines, white blood cells ... diagnosis #algorithm #hepatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
- Blood & BM • ... • Cytopenia -> BM ... and secondary lymphoid ... of large cell lymphoma ... #Leukemia #Hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
autoimmune disorder or lymphoid ... - Monoclonal - Lymphoid ... - Mycoplasma, EBV ... sensitize red blood cells ... hemolytic #anemia #hematology
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia DIAGNOSTIC CRITERIA FOR ICL • Persistent CD4 T-cell lymphopenia •
T-cell count of 300 cells ... Unc119) • Heme (lymphoma ... EBV. CMV. ... ICL #diagnosis #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Amyloidosis • Lymphoma ... acute HIV, HBV, EBV ... gastric tumors • Hematology ... : Lymphoma, Leukemia ... differential #diagnosis #hematology
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