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diagnosis hepatology algorithm lfts causes autoimmune elevated management rheumatology abnormal acute aih antibodies associations autoantibodies biliary chemistry cholangitis cirrhosis dili
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute Liver ... Injury - Differential ... Hepatocellular - Liver ... C, A, E, B, D, EBV ... #Injury #Differential
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... normal - Infection (EBV ... #Patterns #Liver ... #Injury #hepatology ... #differential #
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... Injury → liver ... Injury Differential ... A/B/C/D/E, EBV, ... #Injury #Differential
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... - Differential ... HBV, HCV, HEV, EBV ... #injury #hepatitis ... #differential #
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Elevated Liver Function ... (Drug-induced liver ... injury) • Ischemic ... LouLectures #Liver ... #transaminitis
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Algorithm for Transaminitis ... Elevated #Abnormal #Transaminitis ... Algorithm #diagnosis #hepatology
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
Transaminases / Transaminitis ... - Differential ... HAV, HCV, HEV, EBV ... Trauma: Shock liver ... #Differential #
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Liver Chemistries ... Check Acute viral hepatitis ... Identify Acute Liver ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... HBV, HCV, HEV, EBV ... Alcohol-related liver ... cholangitis Consider liver ... #DrugInduced #Liver
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
cholestasis → Cirrhosis/Liver ... or higher • Liver ... bile ducts Differential ... Diagnosis: • Viral hepatitis ... diagnosis #workup #hepatology
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